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Influence of Age on the Potential Risk of Sudden Death in Asymptomatic Wolff‐Parkinson‐White Syndrome

Identifieur interne : 000182 ( Main/Corpus ); précédent : 000181; suivant : 000183

Influence of Age on the Potential Risk of Sudden Death in Asymptomatic Wolff‐Parkinson‐White Syndrome

Auteurs : Béatrice Brembilla-Perrot ; Ioana Holban ; Pierre Houriez ; Olivier Claudon ; Daniel Beurrier ; Anne Claire Vancon

Source :

RBID : ISTEX:26A4B1A92BDFDB5AAFF13F09F7BFB53D503075E6

English descriptors

Abstract

BREMBILLA‐PERROT, B., et al.: Influence of Age on the Potential Risk of Sudden Death in Asymptomatic Wolff‐Parkinson‐White Syndrome. Sudden death might be the first event in patients with asymptomatic WPW. The purpose of the study was to know if the age of the patient modifies the electrophysiological characteristics of asymptomatic WPW. Transesophageal stimulation was performed on 92 asymptomatic WPW patients from the following age groups: 10–69 years (n =14), 20–29 years (n = 33), 30–39 years (n = 15), 40–49 years (n = 17), and 50–69 years (n = 13). The procedure consisted of atrial pacing up to the second AV block, programmed atrial stimulation using one and two extrastimuli delivered on two driven rhythms in the control state, and after infusion of isoproterenol. In the five age groups, paroxysmal junctional tachycardia occurred, respectively, in 1 (7%), 1 (3%), 2 (13%), 2 (12%) patients, and not at all in the oldest group. AF > 1 minute occurred, respectively, in 3 (21%), 9 (27%), 5 (33%), 3 (18%), and 4 (31%) patients. The dangerous form of WPW (rapid conduction in the Kent bundle > 240/min in the control state or > 300/min after isoproterenol + AF induction) occurred, respectively, in 3 (21%), 9 (27%), 4 (27%), 1 (6%), and 3 (23%) patients. In conclusion, electrophysiological data of asymptomatic WPW are not modified by age of the patient. Elderly patients remain at risk of a dangerous form of WPW; systematic evaluation of WPW is recommended in patients with an active life independent of age.

Url:
DOI: 10.1046/j.1460-9592.2001.01514.x

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ISTEX:26A4B1A92BDFDB5AAFF13F09F7BFB53D503075E6

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<unparsedAffiliation>Department of Cardiology, CHU of Brabois, Vandoeuvre, France</unparsedAffiliation>
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<keyword xml:id="k1">Wolff‐Parkinson‐White syndrome</keyword>
<keyword xml:id="k2">sudden death</keyword>
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<b>BREMBILLA‐PERROT, B.,
<sc>et al.</sc>
: Influence of Age on the Potential Risk of Sudden Death in Asymptomatic Wolff‐Parkinson‐White Syndrome.</b>
Sudden death might be the first event in patients with asymptomatic WPW. The purpose of the study was to know if the age of the patient modifies the electrophysiological characteristics of asymptomatic WPW. Transesophageal stimulation was performed on 92 asymptomatic WPW patients from the following age groups: 10–69 years (
<span type="mathematics">n =14</span>
), 20–29 years (
<span type="mathematics">n = 33</span>
), 30–39 years (
<span type="mathematics">n = 15</span>
), 40–49 years (
<span type="mathematics">n = 17</span>
), and 50–69 years (
<span type="mathematics">n = 13</span>
). The procedure consisted of atrial pacing up to the second AV block, programmed atrial stimulation using one and two extrastimuli delivered on two driven rhythms in the control state, and after infusion of isoproterenol. In the five age groups, paroxysmal junctional tachycardia occurred, respectively, in 1 (7%), 1 (3%), 2 (13%), 2 (12%) patients, and not at all in the oldest group. AF > 1 minute occurred, respectively, in 3 (21%), 9 (27%), 5 (33%), 3 (18%), and 4 (31%) patients. The dangerous form of WPW (rapid conduction in the Kent bundle > 240/min in the control state or > 300/min after isoproterenol + AF induction) occurred, respectively, in 3 (21%), 9 (27%), 4 (27%), 1 (6%), and 3 (23%) patients. In conclusion, electrophysiological data of asymptomatic WPW are not modified by age of the patient. Elderly patients remain at risk of a dangerous form of WPW; systematic evaluation of WPW is recommended in patients with an active life independent of age.</p>
<!--

(PACE 2001; 24:1514&ndash;1518)

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<dateIssued encoding="w3cdtf">2001-10</dateIssued>
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<abstract lang="en">BREMBILLA‐PERROT, B., et al.: Influence of Age on the Potential Risk of Sudden Death in Asymptomatic Wolff‐Parkinson‐White Syndrome. Sudden death might be the first event in patients with asymptomatic WPW. The purpose of the study was to know if the age of the patient modifies the electrophysiological characteristics of asymptomatic WPW. Transesophageal stimulation was performed on 92 asymptomatic WPW patients from the following age groups: 10–69 years (n =14), 20–29 years (n = 33), 30–39 years (n = 15), 40–49 years (n = 17), and 50–69 years (n = 13). The procedure consisted of atrial pacing up to the second AV block, programmed atrial stimulation using one and two extrastimuli delivered on two driven rhythms in the control state, and after infusion of isoproterenol. In the five age groups, paroxysmal junctional tachycardia occurred, respectively, in 1 (7%), 1 (3%), 2 (13%), 2 (12%) patients, and not at all in the oldest group. AF > 1 minute occurred, respectively, in 3 (21%), 9 (27%), 5 (33%), 3 (18%), and 4 (31%) patients. The dangerous form of WPW (rapid conduction in the Kent bundle > 240/min in the control state or > 300/min after isoproterenol + AF induction) occurred, respectively, in 3 (21%), 9 (27%), 4 (27%), 1 (6%), and 3 (23%) patients. In conclusion, electrophysiological data of asymptomatic WPW are not modified by age of the patient. Elderly patients remain at risk of a dangerous form of WPW; systematic evaluation of WPW is recommended in patients with an active life independent of age.</abstract>
<subject lang="en">
<genre>Keywords</genre>
<topic>Wolff‐Parkinson‐White syndrome</topic>
<topic>sudden death</topic>
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<title>Pacing and Clinical Electrophysiology</title>
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<genre type="Journal">journal</genre>
<identifier type="ISSN">0147-8389</identifier>
<identifier type="eISSN">1540-8159</identifier>
<identifier type="DOI">10.1111/(ISSN)1540-8159</identifier>
<identifier type="PublisherID">PACE</identifier>
<part>
<date>2001</date>
<detail type="volume">
<caption>vol.</caption>
<number>24</number>
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<detail type="issue">
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<number>10</number>
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<extent unit="pages">
<start>1514</start>
<end>1518</end>
<total>5</total>
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